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- Dr.Raman Venkataramanan, school of pharmacy professor, has become the faculty advisor for AAPS student chapter at the university of pittsburgh.
- Ayman Akil, AAPS chapter chair, has received a certificate of appreciation from AAPS acknowledging his outstanding performance as AAPS student chair at the University of Pittsburgh.
- Nisanne Ghonem, School of Pharmacy PhD candidate, has received a renewal of her T32 fellowship from the University of Pittsburgh Clinical and Translational Science Institute. She has also received the Provost Development Fund Fellowship from the Office of the Provost. These fellowships cover tuition, and in addition, a stipend, travel allowance, and dissertation-related research materials for the 2009-2010 academic year.
Ghonem's research explores the ability of an investigational agent to protect against ischemic-induced hepatic injury in orthotopic liver transplantation.
- School of Pharmacy PhD student Jennifer Bonner received a renewal of her T32 fellowship from the University's Clinical and Translational Sciences Institute (CTSI) for June 1, 2009, to May 31, 2010. The fellowship is in support of her work examining intestinal first-pass metabolism of drugs in small bowel of multivisceral transplant patients. The title of her study is "Evaluation of intestinal CYP3A4/5 and p-glycoprotein function in small bowel transplant recipients.
- PhD student Mark Donnelly won one of four poster awards at the 11th International Winter Eicosanoid Conference, held in Baltimore, Md., on March 8-11, 2009. His poster was titled, “CYP4F2 Polymorphic Variants Are Linked to 20-HETE CSF Levels and Neuropsychological Outcomes in aSAH Patients.” Mark works in the lab of Dr. Samuel Poloyac, associate professor of pharmaceutical sciences.
- Nisanne Ghonem, and PhD candidate, working under the supervision of Professor Raman Venkataramanan, has presented her research findings at the Joint EASL-AASLD Monothematic Conference on Nuclear Receptors and Liver Disease, held in Vienna, Austria, from February 27 to March 1, 2009. The title of her presentation was “Treprostinil, a prostacyclin analog, activates PPARα in hepatocytes: Implications in preventing ischemia-reperfusion injury in liver transplantation." Ghonem had been selected as a presenting author of one of the best 50 scored abstracts.
-Shashi Sriram, PhD student, has had his first authored review paper accepted for publication in Chemistry and Biology. Sriram works in Dr. Yong Tae Kwon's lab, which focuses on the ubiquitin-dependent N-end rule pathway. Sriram paper is titled, "Multivalency-Assisted Control of Intracellular Signaling Pathways: Application for Ubiquitin-Dependent N-End Rule Pathway."
- FDA Pharmacometrics, Office of Clinical Pharmacology and Division of Cardiorenal Drug Products, jointly received a Critical Path Research Grant from CDER to conduct research on public health policy pertaining to anti-hypertensives use. This grant is awarded to Ms. Yuyan Jin at the University of Pittsburgh.
Yuyan is a PhD student in the Department of Pharmaceutical Sciences in the School of Pharmacy. She is working under the supervision of Dr. Robert Bies, specifically, on nonlinear mixed effects and Bayesian approaches to PK/PD and disease progress modeling and simulation. Jin received her masters in pharmaceutics from the China Pharmaceutical University in June of 2004 and joined the University of Pittsburgh in early 2006.
Yuyan has received several awards including a student travel award from the American College of Clinical Pharmacology in conjunction with her presentation of adherence-related estimation of population PK parameters for escitalopram. She has published on this work in the Journal of Clinical Pharmacology. Her focus in the project with FDA will be to use Monte Carlo clinical trial simulation techniques to examine the current practice for blood pressure measurement and monitoring. This will provide an explicit quantification of the errors occurring in typical practice and allow for various interventions to be tested virtually with respect to improving clinical decision-making in the area of blood pressure control.
- November 16th-20th, 2008: Four student chapter members attended the 2008 AAPS Annual Meeting and Exposition. The students have all presented posters about their research work.
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